Dose-Related Enhancement of Mood and Cognition in Smokers Administered Nicotine Nasal Spray

Recycling of hard-core smokers with nicotine nasal spray.

The primary aim of this smoking cessation study was to evaluate the effect of long-term treatment with nicotine nasal spray in a group of hard-core smokers. A further aim was to compare the effect of ad libitum with fixed dosage of nasal nicotine spray. Eighty nine smokers, failures from two earlier studies with nicotine patches, were enrolled in an open smoking cessation study with nicotine na...

Effects of nicotine patch or nasal spray on nicotine and cotinine concentrations in pregnant smokers.

OBJECTIVE To examine the short-term effects of the nicotine patch or nasal spray on measures of nicotine exposure, withdrawal symptoms, and on maternal and fetal heart rates in pregnant smokers. METHODS We measured nicotine/cotinine concentrations and maternal and fetal heart rates during an 8-h monitoring session while smoking and again after 4 days of nicotine patch (15 mg/16 h), nasal spra...

Review of Nicotine nasal spray neither effective nor well-tolerated by adolescent smokers

Nicotine nasal spray neither effective nor well-tolerated by adolescent smokers.

A single dose of oxytocin nasal spray improves higher-order social cognition in schizophrenia.

Schizophrenia is associated with significant impairments in both higher and lower order social cognitive performance and these impairments contribute to poor social functioning. People with schizophrenia report poor social functioning to be one of their greatest unmet treatment needs. Recent studies have suggested the potential of oxytocin as such a treatment, but mixed results render it uncert...